Wichtige Dokumente

Gesamtdokumentation anzeigen

Fortfahren mit

218840

Caspase-8 Inhibitor II

Name: Caspase-8 Inhibitor II
Brand: MM

InSolution

Synonym(e):

InSolution Caspase-8 Inhibitor II, Granzyme B Inhibitor III; Z-IE(OMe)TD(OMe)-FMK

Anmelden zur Ansicht der Organisations- und Vertragspreise.

Größe auswählen

Ansicht ändern

Größe/SKU	Verfügbarkeit	Preis

Über diesen Artikel

Empirische Formel (Hill-System):

C₃₀H₄₃FN₄O₁₁

Molekulargewicht:

654.68

NACRES:

NA.54

UNSPSC Code:

12352200

Form:

liquid

Storage condition:

OK to freeze, desiccated (hygroscopic), protect from light

Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Technischer Dienst

Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.

Unterstützung erhalten

Eigenschaften

Quality Segment

100

form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

shipped in

wet ice

storage temp.

−20°C

Beschreibung

General description

A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO. Z-IETD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-8 (MACH, FLICE, Mch5). Also inhibits granzyme B.

Biochem/physiol Actions

Cell permeable: yes

Primary Target
caspase-8

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Physical form

A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218759) in DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

≥98% (HPLC)

Other Notes

Martin, D.A., et al. 1998. J. Biol. Chem.273, 4345.
Sweeney, E.A., et al. 1998. FEBS Lett.425, 61.

Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F*

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Ähnliche Artikel vergleichen

Vollständigen Vergleich anzeigen

Unterschiede anzeigen

1 of 1

Dieser Artikel	218759	218753	264155
Sigma-Aldrich 218840 Caspase-8 Inhibitor II	Sigma-Aldrich 218759 Caspase-8-Inhibitor II	Sigma-Aldrich 218753 Caspase-5 Inhibitor I	Sigma-Aldrich 264155 Caspase-3-Inhibitor II
description InSolution	description The Caspase-8 Inhibitor II controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications.	description Z-WEHD-FMK is a cell-permeable, potent, irreversible caspase-5 inhibitor, that also inhibits the activity of Caspase 1, 4, and 8.	description The Caspase-3 Inhibitor II, also referenced under CAS 210344-95-9, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications.
form liquid	form powder	form solid	form solid
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 200
manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®	manufacturer/tradename Calbiochem^®
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
storage condition desiccated (hygroscopic), protect from light, OK to freeze	storage condition desiccated, OK to freeze	storage condition OK to freeze, desiccated	storage condition OK to freeze, desiccated
shipped in wet ice	shipped in ambient	shipped in ambient	shipped in ambient

Still not finding the right product?

Explore all of our products under Caspase-8 Inhibitor II

Lagerklasse

10 - Combustible liquids

Was ist los?

WGK 1

Flammpunkt (°F)

188.6 °F - (refers to pure substance)

Flammpunkt (°C)

87 °C - (refers to pure substance)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumente section.

Wenn Sie Hilfe benötigen, wenden Sie sich bitte an Kundensupport

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.