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230790

Chymostatin

Selective neurokinin-1 (NK1) receptor antagonist, solid,powder

Synonym(e):

Chymostatin

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Größe/SKUVerfügbarkeitPreis
5 mg
Warenkorb auf Verfügbarkeit prüfen
€ 109,00
10 mg
Warenkorb auf Verfügbarkeit prüfen
€ 221,00
25 mg
Warenkorb auf Verfügbarkeit prüfen
€ 459,00

Über diesen Artikel

CAS-Nummer:
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Form:
solid, powder
Storage condition:
OK to freeze

€ 109,00


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Produktname

Chymostatin, Contains chymostatin "A" as a major form.

Quality Segment

description

RTECS - GC3047700

form

solid, powder

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white to slightly yellow

solubility

5% glacial acetic acid: 10 mg/mL, DMSO: 20 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

N7C(CCNC7=N)[C@H](NC(=O)N[C@@H](Cc9ccccc9)C(=O)O)C(=O)N[C@@H]([C@H](CC)C)C(=O)N[C@@H](Cc8ccccc8)C=O.N4C(CCNC4=N)[C@H](NC(=O)N[C@@H](Cc6ccccc6)C(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc5ccccc5)C=O.N1C(CCNC1=N)[C@H](NC(=O)N[C@@H](Cc3ccccc3)C(=O)O)C(=O)N[C@@

InChI

1S/2C31H41N7O6.C30H39N7O6/c1-19(2)15-24(27(40)34-22(18-39)16-20-9-5-3-6-10-20)35-28(41)26(23-13-14-33-30(32)36-23)38-31(44)37-25(29(42)43)17-21-11-7-4-8-12-21;1-3-19(2)25(27(40)34-22(18-39)16-20-10-6-4-7-11-20)37-28(41)26(23-14-15-33-30(32)35-23)38-31(44)36-24(29(42)43)17-21-12-8-5-9-13-21;1-18(2)24(26(39)33-21(17-38)15-19-9-5-3-6-10-19)36-27(40)25(22-13-14-32-29(31)34-22)37-30(43)35-23(28(41)42)16-20-11-7-4-8-12-20/h3-12,18-19,22-26H,13-17H2,1-2H3,(H,34,40)(H,35,41)(H,42,43)(H3,32,33,36)(H2,37,38,44);4-13,18-19,22-26H,3,14-17H2,1-2H3,(H,34,40)(H,37,41)(H,42,43)(H3,32,33,35)(H2,36,38,44);3-12,17-18,21-25H,13-16H2,1-2H3,(H,33,39)(H,36,40)(H,41,42)(H3,31,32,34)(H2,35,37,43)/t22-,23?,24-,25-,26-;19-,22-,23?,24-,25-,26-;21-,22?,23-,24-,25-/m000/s1

InChI key

QJIJPLFVFWXMGK-KSPFWWQASA-N

General description

Cell permeable: No

Product does not compete with ATP.

Reversible: No

Chymostatin is a naturally occurring inhibitor of serine proteases with chymotryptic-like specificity. This tetrapeptide inhibitor is produced by various species of Streptomyces bacteria. Chymostatin is used as an inhibitor of MC chymase and is also capable of inhibiting several other proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, and lysosomal cysteine proteinases such as cathepsins B, H, andL. Itcontains chymostatin "A" as a major form.

Application

Chymostatin has been used as a:

  • cysteine protease inhibitor in thesubstrate to measure the activated FX (FXa) activity
  • protease inhibitor in enzyme purificationlysis buffer
  • protease inhibitor for ISW2 protein complexpurification

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxizität: Standard-Handhabung (A)

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Dieser Artikel
EI6T0501274666
description

Contains chymostatin "A" as a major form.

description

-

description

≥98.5%

description

≥98%

form

powder, solid

form

-

form

powder or crystals

form

solid

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Chemicon®

manufacturer/tradename

-

manufacturer/tradename

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

room temp

storage temp.

room temp

solubility

5% glacial acetic acid: 10 mg/mL, DMSO: 20 mg/mL

solubility

-

solubility

ethanol: 50 mg/mL

solubility

-

storage condition

OK to freeze

storage condition

-

storage condition

-

storage condition

-


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Lagerklasse

11 - Combustible Solids

Was ist los?

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable



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