8.56053

H-Gly-2-ClTrt resin

Novabiochem^®

• Synonym(e): Glycine-2-Chlorotrityl Resin
• NACRES: NA.22
• UNSPSC Code: 12352209

Eigenschaften

• Quality Segment: 200
• product line: Novabiochem^®
• form: beads
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• storage temp.: 2-8°C

Beschreibung

General description

Pre-loaded resin for synthesis of protected peptide acids containing a C-terminal glycine amino-acid residue by Fmoc SPPS. Cleavage of the protected peptide is effected by treatment with 1% TFA in DCM or 20% TFE in DCM

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Application

• Development of peg-peptide conjugate based curcumin delivery systems: Discusses the use of H-Gly-2-ClTrt resin and Rink amide MBHA resin to synthesize side-chain-protected and deprotected peptides, highlighting challenges in synthesizing high-molecular-weight peptides using 2-chlorotrityl resin. (G Aydoğan, 2022).

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.90 mmol/g
Swelling Volume (in DMF): lot specific result
Identity (of the substitution): passes test
The polymer matrix is copoly (styrene-1 % DVB), 200 - 400 mesh.

Other Notes

Replaces: 04-12-2800

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable