ABE607

Anti-APOBEC3G Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): DNA dC->dU-editing enzyme APOBEC-3G, APOBEC-related cytidine deaminase, APOBEC-related protein, ARCD, APOBEC-related protein 9, ARP-9, CEM-15, CEM15, Deoxycytidine deaminase
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC, WB
• Citations: 1

Eigenschaften

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• technique(s): immunohistochemistry: suitable, western blot: suitable
• UniProt accession no.: Q9HC16
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... APOBEC3G(60489)

Beschreibung

General description

DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G) is a member of the cytidine and deoxycytidylate deaminase family. APOBEC3G is a multi-isoform member of the cytidine deaminase family of enzymes that act on monomeric nucleoside and nucleotide substrates. Similar to TRIM5 alpha which targets incoming retroviral capsids, APOBEC3G plays an important role in cellular defense against retroviral infection. It is expressed in spleen, testes, ovary, peripheral blood leukocytes, and several tumor cell lines.

~46 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to the N-terminus of human APOBEC3G.

Application

Detect APOBEC-3G using this rabbit polyclonal antibody, Anti-APOBEC3G Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 1 µg/mL from a representative lot detected APOBEC3G in human spleen tissue.

Biochem/physiol Actions

This antibody recognizes the N-terminus of APOBEC3G.

Analysis Note

Evaluated by Western Blotting/Peptide Inhibition Assay Analysis in Caco-2 cell lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 5 µg/mL of this antibody detected APOBEC3G in 15 µg of Caco-2 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• Was ist los?: WGK 2