FCMAB192F

Milli-Mark^® Anti-CD30-FITC Antibody, clone Ber-H2

clone Ber-H2, Milli-Mark^®, from mouse

• Synonym(e): Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Lymphocyte activation antigen CD30, Ki-1 antigen
• UNSPSC Code: 12352203
• NACRES: NA.44
• eCl@ss: 32160702
• Conjugate: FITC conjugate
• Clone: Ber-H2, monoclonal
• Application: FACS
• Citations: 1

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• conjugate: FITC conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: Ber-H2, monoclonal
• species reactivity: human
• manufacturer/tradename: Milli-Mark^®
• technique(s): flow cytometry: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_001234
• UniProt accession no.: P28908
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... TNFRSF8(943)

Beschreibung

General description

120 kDa (de Bruin, 1995)

CD30 is a transmembrane cytokine receptor belonging to the tumor necrosis factor (TNF) receptor superfamily. Mature CD30 has a molecular mass of 120 kDa and is derived from a 90 kDa precursor protein (de Bruin, 1995). The extracellular domain of CD30 is homologous to that of TNF receptor superfamily members, whereas there is no homology in teh cytoplasmic domain, suggesting major differences in signaling mechanisms (Falini, 1995). CD30 expression is found on Hodgkin and Reed-Sternberg (H-RS) cells, and on activated B and T lymphocytes (de Bruin, 1995). The antibody from the Ber-H2 hybridoma cell line was included in the Fourth International Workshop on Human Leukocyte Differentiation Antigens and was found to belong to the CD30 cluster (Schwarting, 1989).

Immunogen

Co-cell line established from a human with Hodgkin′s disease of T-cell lineage.

Application

Milli-Mark Anti-CD30-FITC Antibody, clone Ber-H2 detects level of CD30 & has been published & validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Biochem/physiol Actions

Antibody recognizes Human CD30 antigen.

Physical form

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Preparation Note

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
Jurkat cells

Evaluated by flow cytometry using Jurkat cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• Was ist los?: WGK 2