GF342
LIF,
Human Recombinant Animal Free
Synonym(e):
Leukemia Inhibitory Factor, Emfilermin, MLPLI, HILDA, D-FACTOR
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Über diesen Artikel
UNSPSC Code:
12352202
NACRES:
NA.75
eCl@ss:
32160405
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
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Unterstützung erhaltenGeneral description
LIF is a pleiotrophic factor produced by multiple cell types including T cells, myelomoncytic lineages, fibroblasts, liver, heart and melanoma. LIF promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Other activities include the stimulation of acute phase protein synthesis by hepatocytes, stimulation of differentiation of cholinergic nerves, and suppression of adipogenesis by inhibiting the lipoprotein lipase in adipocytes. While human LIF is active on mouse cells and is widely used in the maintenance of murine ESC to prevent spontaneous differentiation, mouse LIF is not active on human cells due to its inability to bind to the human LIF receptor.
Recombinant human LIF is a 19.6 kDa protein containing 180 amino acids residues including three disulfide bonds.
Recombinant human LIF is a 19.6 kDa protein containing 180 amino acids residues including three disulfide bonds.
Analysis Note
Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤0.1 ng/ml, corresponding to a specific activity of ≥1 x 10^7 units/mg.
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Dieser Artikel | |||
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| description - | description recombinant, expressed in rice, 500 μg/mL | description - | description - |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
| impurities <0.1 μg/mg protein endotoxin (<1 EU/μg) | impurities <0.05 EU/μg endotoxin | impurities <0.1 μg/mg protein endotoxin (<1 EU/μg) | impurities <0.1 μg/mg protein endotoxin (<1 EU/μg) |
| storage temp. -10 to -25°C | storage temp. −70°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 1
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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