74147

Iohexol

analytical standard

• Synonym(e): 5-[N-(2,3-Dihydroxypropyl)-acetamino]-2,4,6-triiod-N,N′-bis-(2,3-dihydroxypropyl)-isophthalamid
• Empirische Formel (Hill-System): C₁₉H₂₆I₃N₃O₉
• CAS-Nummer: 66108-95-0
• Molekulargewicht: 821.14
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329765500
• EC Number: 266-164-2
• Beilstein/REAXYS Number: 2406632
• MDL number: MFCD00077732
• eCl@ss: 25140904

Eigenschaften

• grade: analytical standard
• Quality Segment: 100
• assay: ≥95.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
• impurities: ≤6.0% water
• application(s): clinical testing
• format: neat
• SMILES string: IC1=C(C(NCC(O)CO)=O)C(I)=C(C(NCC(CO)O)=O)C(I)=C1N(CC(CO)O)C(C)=O
• InChI: 1S/C19H26I3N3O9/c1-8(29)25(4-11(32)7-28)17-15(21)12(18(33)23-2-9(30)5-26)14(20)13(16(17)22)19(34)24-3-10(31)6-27/h9-11,26-28,30-32H,2-7H2,1H3,(H,23,33)(H,24,34)
• InChI key: NTHXOOBQLCIOLC-UHFFFAOYSA-N

Beschreibung

General description

Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker to determine the glomerular filtration rate (GFR) which measures the level of kidney function. It finds applications in angiographic and urography procedures.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Iohexol may be used as an internal standard for the determination of iohexol in human plasma, serum and urine samples by HPLC-UV method. It may also be used as a model compound to analyze the applicability of iohexol for glomerular filtration rate (GFR) measurement by the plasma clearance of iohexol in investigating renal failure.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable