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ECO TWEEN® 20

greener alternative

viscous liquid

Synonym(e):

TWEEN® 20, Polyethylenglykolsorbitanmonolaurat, Polyoxyethylensorbitanmonolaurat

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250 ML

€ 57,20

1 L

€ 171,00

€ 57,20


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Über diesen Artikel

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12161902
NACRES:
NA.28

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Beschreibung

non-ionic

Qualitätsniveau

Assay

≥40%

Form

viscous liquid

Mol-Gew.

~1228

Zusammensetzung

lauric acid, ≥40% (balance primarily myristic, palmitic, and stearic acids)

Grünere Alternativprodukt-Eigenschaften

Use of Renewable Feedstocks
Design for Degradation
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Konzentration

≥40.0% (GC)

Verunreinigungen

≤3.0% water

Brechungsindex

n20/D 1.468 (lit.)

CMC

0.06 mM (20-25°C)

mp (Schmelzpunkt)

98.9 °C

Säurezahl

≤2.2 mg KOH/g

Hydroxylzahl

96‑108 mg KOH/g

Übergangstemp.

cloud point 76 °C

Löslichkeit

water: 100 mg/mL, clear, faintly yellow to yellow

Dichte

1.095 g/mL at 25 °C (lit.)

HLB

16.7

Grünere Alternativprodukt-Kategorie

SMILES String

CCCCCCCCCCCC(=O)OCCOCC(C1C(C(CO1)OCCO)OCCO)OCCO

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChIKey

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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Dieser Artikel
P9416P7949655205
form

viscous liquid

form

viscous liquid

form

viscous liquid

form

liquid

assay

≥40%

assay

>40% (GC)

assay

-

assay

-

density

1.095 g/mL at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.)

density

1.095 g/mL at 25 °C (lit.)

description

non-ionic

description

non-ionic

description

non-ionic

description

RTECS - TR7400000

CMC

0.06 mM (20-25°C)

CMC

60 mg/L

CMC

0.06 mM (20-25°C)

CMC

59 μM (HLB number 16.7)

solubility

water: 100 mg/mL, clear, faintly yellow to yellow

solubility

water: 100 mg/mL, clear, colorless to yellow

solubility

-

solubility

water: 10%

Allgemeine Beschreibung

ECO TWEEN® 20, also known as Polyoxyethylenesorbitan monolaurate, is a bio-based, nonionic detergent manufactured from a natural fatty acid. This surfactant, derived from natural sources, provides various functional advantages, such as detergency, emulsification, and wetting. Its versatility makes it well-suited for a variety of applications in biochemical and biological research, with common uses including cell lysis, protein extraction, nuclei isolation and cell fractionation.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is a biobased surfactant and is aligned with the 7th principle of Green Chemistry "Use of Renewable Feedstocks" and the 10th principle "Design for Degradation".

TWEEN 20 is a polyoxyethylene sorbitol ester that belongs to the polysorbate family. It is a nonionic detergent having a molecular weight of 1,225 daltons, assuming 20 ethylene oxide units, 1 sorbitol, and 1 lauric acid as the primary fatty acid. The ethylene oxide subunits are responsible for the hydrophilic nature of the surfactant, while the hydrocarbon chains provide the hydrophobic environment. Sorbitol forms the backbone ring to which the ethylene oxide polymers are attached.[1]

Anwendung

Anionisches Reinigungsmittel
TWEEN 20 has been used as a component of:
  • washing buffer and blocking buffer in Western blotting[2]
  • blocking buffer in immunohistochemistry[3]
  • washing buffer in ELISA (enzyme linked immunosorbent assay)[4][5]
  • reaction mixture in PCR (polymerase chain reaction)[6]
TWEEN 20 is a nonionic detergent widely used in biochemical applications. It has been used as an emulsifying agent for the preparation of stable oil-in-water emulsions. TWEEN 20 has been used in pre-extraction of membranes to remove peripheral proteins (used at 2% for extraction of membrane-bound proteins).
TWEEN 20 has been used as a blocking agent for membrane based immunoassays at a typical concentration of 0.05%. TWEEN 20 can be used for lysing mammalian cells at a concentration of 0.005 to 0.5%.

Leistungsmerkmale und Vorteile

  • 100 % Renewable
  • 100 % Bio-based
  • Certified to the USDA BioPreferred Program
  • Lower carbon footprint than petrochemical-based versions
  • High-purity chemical suitable for a wide variety of research applications

Angaben zur Herstellung

TWEEN 20 is miscible in water (100mg/mL), yielding a clear, yellow solution. It is also miscible with alcohol, dioxane, and ethyl acetate. TWEEN 20 is insoluble in liquid paraffin and fixed oils.

Sonstige Hinweise

For additional information on our range of Biochemicals, please complete this form.

Rechtliche Hinweise

ECO TWEEN is a registered trademark of Croda Inc.
TWEEN is a registered trademark of Croda International PLC

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

527.0 °F - Pensky-Martens closed cup

Flammpunkt (°C)

275 °C - Pensky-Martens closed cup


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Die Dokumentenbibliothek aufrufen

Gene expression and immune response kinetics using electroporation-mediated DNA delivery to muscle.
Gr?nevik E et al
The journal of gene medicine, 7(2), 218-227 (2005)
Use of tRNA consensus primers to indicate subgroups of Pseudomonas solanacearum by polymerase chain reaction amplification.
Seal SE et al
Applied and Environmental Microbiology, 58(11), 3759-3761 (1992)
Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways.
Kerwin BA
J. Pharm. Pharm. Sci., 97(8), 2924-2935 (2008)
Ethylene and carbon dioxide production by developing strawberries show a correlative pattern that is indicative of ripening climacteric fruit.
Lannetta PM et al
Physiologia Plantarum, 127.2, 247-259 (2006)
Jennifer Somerfield et al.
Journal of immunology (Baltimore, Md. : 1950), 185(1), 763-768 (2010-06-04)
Biological therapies, even humanized mAbs, may induce antiglobulin responses that impair efficacy. We tested a novel strategy to induce tolerance to a therapeutic mAb. Twenty patients with relapsing-remitting multiple sclerosis received an initial cycle of alemtuzumab (Campath-1H), up to 120

Questions

  1. Why is this 'eco' tween ? CAS 9005-64-5

    1 answer
    1. ECO surfactants are made using bio-based ethylene oxide (EO) from biomass ethanol, so they are completely renewable. Moreover, they are manufactured at a plant which runs on a high proportion of renewable energy, further reducing your carbon footprint when using ECO surfactants. Kindly review the following link for more information: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/123/856/greener-surfactants-fl4874en-ms.pdf

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