18887

Byzen Pro^™ Protein-A-Harz

suitable for affinity chromatography

• NACRES: NA.56
• UNSPSC Code: 13111000
• eCl@ss: 32160703
• Form: suspension

Eigenschaften

• form: suspension
• technique(s): affinity chromatography: suitable, antibody protein purification: suitable
• mean particle size: 70 μm
• storage temp.: 2-8°C

Beschreibung

Application

Byzen Pro^™ Protein A resin is an affinity chromatography medium in which a novel Protein A mutant is used as a ligand. Conventional protein A resins use strongly acidic buffers to elute antibodies, exposing the target antibody to the risks of aggregation and decreased activities. In contrast, this temperature- responding Byzen Pro^™ Protein A resin allows antibodies to be eluted under neutral pH by a simple temperature change. This eliminates any risk of aggregation and decreased activity of the antibody, improving manufacturing efficiency for pharmaceutical antibodies.

Features and Benefits

Typical Product Profile:
Bead Structure, Cross-linked polyvinyl alcohol, Mean Particle Size 70 μm, Max. Back Pressure 0.3 MPa, Flow Rate (Recommended) 125-250 cm/h, pH Range (Recommended) pH 6-8, Ligand: Recombinant Protein A mutant, Ligand Immobilization: Multiple ligation, Dynamic Binding Capacity (20 cm column): 26 g/L (250 cm/h) 34 g/L (125 cm/h), Total Binding Capacity 40 g/L, Binding Temperature Below 10°C, Eluting Temperature 37 to 40°C, Mode of Temperature Change: Conventional heat exchange system can be used.

Legal Information

Byzen Pro is a trademark of Nomadic Bioscience Co., Ltd

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable