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80198

Methoxatin Dinatriumsalz

≥97.0% (HPLC)

Synonym(e):

PQQ, Pyrrolo-chinolin-chinon Dinatriumsalz

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Größe/SKUVerfügbarkeitPreis
10 mg
Warenkorb auf Verfügbarkeit prüfen
€ 283,00
50 mg
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€ 1.160,00

Über diesen Artikel

Empirische Formel (Hill-System):
C14H4N2Na2O8
CAS-Nummer:
Molekulargewicht:
374.17
NACRES:
NA.79
PubChem Substance ID:
UNSPSC Code:
12352005
MDL number:

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Unterstützung erhalten


biological source

fermentation/recombinant

Quality Segment

assay

≥97.0% (HPLC)

form

powder

color

red-brown to deep orange, red-brown to deep red-brown

storage temp.

2-8°C

SMILES string

OC(=O)c1cc(nc2C(=O)C(=O)c3cc([nH]c3-c12)C(=O)O[Na])C(=O)O[Na]

InChI

1S/C14H6N2O8.2Na/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;/q;2*+1/p-2

InChI key

UFVBOGYDCJNLPM-UHFFFAOYSA-L

General description

Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.

Application


  • Safety assessment of a novel, dietary pyrroloquinoline quinone disodium salt (mnemoPQQ): This study investigates the safety profile of Methoxatin disodium salt, which has implications for its application in assay development for clinical and diagnostic purposes. Specifically, it addresses the compound′s use in dietary supplements and potential crossover into clinical assays where safety and toxicity are paramount (Shiojima et al., 2022).


Biochem/physiol Actions

In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.

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Dieser Artikel
D77831864985356
description

≥97.0% (HPLC)

description

≥95.0% (HPLC)

description

acid washed

description

granular, ≥99.9%

assay

≥97.0% (HPLC)

assay

≥95.0% (HPLC)

assay

-

assay

≥99.9%

biological source

fermentation/recombinant

biological source

synthetic

biological source

-

biological source

-

form

powder

form

powder

form

solid

form

granular

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

color

red-brown to deep red-brown, red-brown to deep orange

color

red to deep red

color

-

color

-


Lagerklasse

11 - Combustible Solids

Was ist los?

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

PSA (Persönliche Schutzausrüstung)

Eyeshields, Gloves, type N95 (US)



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Questions

1–3 of 3 Questions  
  1. Can this be used as a Certified Standard or Secondary Standard?

    1 answer
    1. No, this product is not intended for used as an analytical standard. The material has not been tested against any compendial or agency standard.

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  2. What solvents can be used to reconstitute Product 80198, Methoxatin?

    1 answer
    1. Product 80198, Methoxatin disodium salt is soluble in water up to 3 mg/ml. The following reference by Zimmerman, L.B. et al., Analytical Biochemistry, 411 (2), 194-199 (2011) has solubilized the product in 250 μM in HEPES buffer (20 mM, pH 7.0, 290 mOsmol/kg).

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

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