86826

5-Carboxyfluorescein

BioReagent, suitable for fluorescence, ≥95% (HPLC)

• Synonym(e): 5-FAM
• Empirische Formel (Hill-System): C₂₁H₁₂O₇
• CAS-Nummer: 76823-03-5
• Molekulargewicht: 376.32
• UNSPSC Code: 12171500
• NACRES: NA.32
• PubChem Substance ID: 57653195
• MDL number: MFCD00036874
• Beilstein/REAXYS Number: 57037

Eigenschaften

• product line: BioReagent
• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• solubility: DMF: soluble, DMSO: soluble, H₂O: soluble
• fluorescence: λ_ex 492 nm; λ_em 517 nm in 0.1 M Tris pH 8.0
• suitability: suitable for fluorescence
• SMILES string: OC(=O)c1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35
• InChI: 1S/C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21/h1-9,22-23H,(H,24,25)
• InChI key: NJYVEMPWNAYQQN-UHFFFAOYSA-N

Beschreibung

General description

5-Carboxyfluorescein, also known as 5-FAM, is a green fluorescent product. It is derived from cleavage of 5-Carboxyfluorescein diacetate by intracellular esterases. In viable cells, the fluorescent molecule is impermeable to the cellular membrane.

Application

5-Carboxyfluorescein has been used as a payload to study leakage phenomena on sesame (Sesamum indicum L.) and coconut (Cocos nucifera L.) liposomes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Derivate von Fluorescein führen nach Konjugation mit Biopolymeren zu stabilen Verbindungen

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)