The solubility information can be found on the Specification sheet: Solubility (Solvent) Water or 1% Acetic Acid Solubility (Conc) 1.00 - 1.04 mg/ml. Stock solutions are stable for up to 3 months at -20°C.
Fortfahren mit
A1439
Pituitary adenylate cyclase activating polypeptide-38
Synonym(e):
PACAP-38
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
0.1 mg | Warenkorb auf Verfügbarkeit prüfen | € 345,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C203H331N63O53S
CAS-Nummer:
Molekulargewicht:
4534.26
UNSPSC Code:
41106305
NACRES:
NA.32
MDL number:
eCl@ss:
32150313
Form:
powder
Technischer Dienst
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Unterstützung erhaltenform
powder
Quality Segment
composition
Peptide content, ~70%
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... ADCYAP1(116)
General description
Application
Biochem/physiol Actions
Pituitary adenylate cyclase activating polypeptide-38 (PACAP38) is a cardioprotectant and may help in treating radiation-induced heart disease (RIHD). It plays a protective role during oxidative stress in cardiomyocytes. PACAP38 has antioxidant, anti-apoptotic and anti-inflammatory property. It is implicated in the pathophysiology of migraine and cluster headache.
PACAP-38 is a neuropeptide that has substantial sequence homology to vasoactive intestinal peptide (VIP). It is reported to serve as a neuronal survival factor.
Other Notes
Lyophilized from 0.1% TFA in H2O
1 of 1
Dieser Artikel | ||
|---|---|---|
| description - | description More active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50 = 7 nM). | description Increases cAMP levels in a dose-dependent manner (EC50 = 4.7 nM). |
| form powder | form solid | form solid |
| Quality Level 200 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. - |
| composition Peptide content, ~70% | composition - | composition - |
| Gene Information human ... ADCYAP1(116) | Gene Information - | Gene Information - |
Lagerklasse
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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How can stock solutions for item A1439, Pituitary adenylate cyclase activating polypeptide-38, be reconstituted and stored?
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