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A3352
Acyl-Coenzym A-Synthetase aus Pseudomonas sp.
≥2 units/mg protein
Synonym(e):
Acid: CoA ligase (AMP-forming)
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 unit | Warenkorb auf Verfügbarkeit prüfen | € 239,00 |
10 units | Warenkorb auf Verfügbarkeit prüfen | € 1.180,00 |
Über diesen Artikel
CAS-Nummer:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-747-5
MDL number:
EG-Nummer:
Specific activity:
≥2 units/mg protein
Technischer Dienst
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Unterstützung erhaltenGeneral description
Acyl-coenzyme A synthetase belongs to adenylate-forming enzymes superfamily. It has a conserved adenosine triphosphate/adenosine monophosphate (ATP/AMP) binding motif.
Application
Acyl-coenzyme A Synthetase may be used to study fatty acid metabolism and lipid metabolism. It has been used to study its interaction with fatty acid transport proteins, which has been found to be involved in the efficient cellular uptake of long-chain fatty acids in adipocytes .
Acyl-coenzyme A (coA) synthetase from Pseudomonas sp. has been used:
- as ligase in the synthesis of mevalonate derivatives of adenosine triphosphate (ATP)
- in in vitro fatty acylation assays
- in the synthesis of (14C)Vernoloyl-CoA (Va-CoA),(3) bisphosphonates derivatives of ATP(4) and (3H)Palmitate-CoA
Biochem/physiol Actions
Acyl coenzyme A synthetase proteins are involved in regulating and facilitating long-chain fatty acid transport in mammalian cells .
Acyl-coenzyme A (CoA) synthetase (ACS) enzyme catalyzes a two-step thioesterification reaction involving the conversion of free fatty acids (FAs) to CoA esters. The substrate for ACS varies from two carbon to 26 carbon FAs. It is involved in the activation of FAs for lipid metabolism and enables FA to participate in various cellular metabolic pathways.
Other Notes
1 U bildet 1.0 μmol AMP und Oleoyl-Coenzym A aus ATP und Oleat bei pH 8.1 und 25 °C in Anwesenheit von Coenzym A.
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Dieser Artikel | |||
|---|---|---|---|
| description ≥2 units/mg protein | description BioReagent, suitable for cell culture | description ≥90% (HPLC) | description ≥85% |
| specific activity ≥2 units/mg protein | specific activity - | specific activity - | specific activity - |
| form powder | form powder | form - | form - |
| shipped in dry ice | shipped in - | shipped in - | shipped in - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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