A7236

Anacardinsäure

Histone Acetyl transferase (HAT) inhibitor, powder

• Synonym(e): 2-Hydroxy-6-pentadecyl-benzoesäure, 22:0-Anacardsäure, 6-Pentadecyl-salicylsäure
• Empirische Formel (Hill-System): C₂₂H₃₆O₃
• CAS-Nummer: 16611-84-0
• Molekulargewicht: 348.52
• UNSPSC Code: 12352106
• PubChem Substance ID: 329770923
• NACRES: NA.77
• MDL number: MFCD07368254
• Form: powder
• Storage condition: protect from light

Eigenschaften

• Produktname: Anacardinsäure,
• form: powder
• Quality Segment: 100
• storage condition: protect from light
• color: white to beige
• solubility: DMSO: ≥20 mg/mL
• storage temp.: −20°C
• SMILES string: CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O
• InChI: 1S/C22H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-17-15-18-20(23)21(19)22(24)25/h15,17-18,23H,2-14,16H2,1H3,(H,24,25)
• InChI key: ADFWQBGTDJIESE-UHFFFAOYSA-N

Beschreibung

Application

Anacardic acid has been used:

• as a histone acetylase (HAT) inhibitor to study its effects on rat cortical neurons
• as a positive control in acetylation assay in vitro
• as an acetylase inhibitor to study its effects on the ribonucleic acid export 1 (Rae-1) protein acetylation that was transfected in human embryonic kidney cells

Biochem/physiol Actions

Anacardic acid is a natural bioactive compound derived from the nutshell of Anacardium occidentale. It possesses anti-fungal, anti-bacterial, anti-termite, and molluscicidales activities. Anacardic acid acts as a therapeutic agent against obesity, cancer, inflammatory disorders, and oxidative damage. It functions as an inhibitor of various enzymes such as lipoxygenase (LOX-1), xanthine oxidase, nuclear factor κ B (NFκB) kinase, tyrosinase, and ureases.

Anacardsäure ist ein HAT (Histon-Acetyltransferase)-Inhibitor.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable