A8728

Anti-phospho-β-Arrestin (pSer⁴¹²) antibody produced in rabbit

affinity isolated antibody, aqueous solution

• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD06411866
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: -

Eigenschaften

• biological source: rabbit
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: aqueous solution
• species reactivity: rat, mouse
• technique(s): western blot: suitable
• UniProt accession no.: P29067
• shipped in: dry ice
• storage temp.: −70°C
• target post-translational modification: phosphorylation (pSer412)
• Gene Information: mouse ... Arrb2(216869) ; rat ... LOC288930(288930)

Beschreibung

General description

β-arrestin-1 is a scaffold protein that is highly expressed in the central nervous system. This adaptor protein regulates mitogenic signaling, and also mediates the desentization and internalization of G protein coupled receptors (GPCRs).
Rabbit Anti-phospho-β-Arrestin (pSer412) antibody detects mouse and rat β-arrestin-1. The antibody is also expected to react with human and cow antigens due to the high degree of homology (77%).

Immunogen

synthetic phosphopeptide derived from the region of rat β-arrestin-1 that contains serine 412.

Application

Rabbit Anti-phospho-beta-Arrestin (pSer412) antibody can be used for western blot assays.

Physical form

Solution in Dulbecco′s PBS, pH 7.3 with 1 mg/mL BSA and 0.05% Sodium azide.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids