A8981

AS-252424

≥98% (HPLC), solid

• Synonym(e): 5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione
• Empirische Formel (Hill-System): C₁₄H₈FNO₄S
• CAS-Nummer: 900515-16-4
• Molekulargewicht: 305.28
• UNSPSC Code: 12352200
• PubChem Substance ID: 329771025
• MDL number: MFCD11045281
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• assay: ≥98% (HPLC)
• form: solid
• color: yellow
• solubility: DMSO: >20 mg/mL
• storage temp.: 2-8°C
• SMILES string: Oc1cc(F)ccc1-c2ccc(\C=C3\SC(=O)NC3=O)o2
• InChI: 1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6+
• InChI key: OYYVWNDMOQPMGE-WUXMJOGZSA-N

Beschreibung

Biochem/physiol Actions

AS-252424 is a potent and selective phosphoinositide 3-kinase PI3Kγ inhibitor with IC₅₀ = 30 nM in a mouse model.

AS-252424 is a potent and selective phosphoinositide 3-kinase PI3Kγ inhibitor.

Features and Benefits

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)