The product impurities are not identified or quantified. Please see the product specification sheet:
https://www.sigmaaldrich.com/specification-sheets/457/256/A9043-BULK________SIGMA____.pdf.
Fortfahren mit
A9043
S-Acetylthioglykolsäure-N-hydroxysuccinimid-Ester
≥95% (TLC), powder
Synonym(e):
(Acetylthio)-essigsäure-N-succinimidylester, N-Succinimidyl-S-acetylthioglykolat, S-Acetylthioglycolsäure-NHS-ester
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 43,40 |
50 mg | Warenkorb auf Verfügbarkeit prüfen | € 92,70 |
100 mg | Warenkorb auf Verfügbarkeit prüfen | € 153,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C8H9NO5S
CAS-Nummer:
Molekulargewicht:
231.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
7815491
Assay:
≥95% (TLC)
Form:
powder
Technischer Dienst
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Unterstützung erhaltenQuality Segment
assay
≥95% (TLC)
form
powder
solubility
acetonitrile: 50 mg/mL, DMF: soluble
functional group
imide, thioester
storage temp.
−20°C
SMILES string
CC(=O)SCC(=O)ON1C(=O)CCC1=O
InChI
1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3
InChI key
FLCQLSRLQIPNLM-UHFFFAOYSA-N
Application
Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Other Notes
Note that the ester couples very efficiently to primary amines compared to other thiolating reagents. In addition, this reagent will neutralize original amine positive charge.
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Dieser Artikel | |||
|---|---|---|---|
| description ≥95% (TLC), powder | description suitable for fluorescence, ≥95.0% (coupling assay to aminopropyl silica gel) | description ≥98%, powder | description ≥95% (TLC), powder |
| assay ≥95% (TLC) | assay ≥95.0% (coupling assay to aminopropyl silica gel) | assay ≥98% | assay ≥95% (TLC) |
| solubility acetonitrile: 50 mg/mL, DMF: soluble | solubility DMSO: soluble, DMF: soluble | solubility DMF: soluble (lit.)(lit.), chloroform: 100 mg/mL | solubility DMF: 25 mg/mL |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| form powder | form - | form powder | form powder |
| functional group thioester, imide | functional group - | functional group NHS ester | functional group - |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Hello, Could you tell me the percentage of impurities and define specifically which impurities we can find in this reagent ? Thank you,
1 answer-
Helpful?
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