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A9285
α1-Antichymotrypsin from human plasma
≥92.5% (SDS-PAGE), lyophilized powder
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
0.1 mg | Warenkorb auf Verfügbarkeit prüfen | € 206,00 |
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Technischer Dienst
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Unterstützung erhaltenbiological source
human plasma
Quality Segment
assay
≥92.5% (SDS-PAGE)
form
lyophilized powder
mol wt
55-66 kDa
technique(s)
microbiological culture: suitable
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... SERPINA3(12)
General description
α1-Antichymotrypsin (α1-ACT) is also known as serpin peptidase inhibitor, clade A member 3 (SERPINA3). It is a 68 kDa serine protease inhibitor, secreted by the liver. It belongs to the serpin superfamily of protease inhibitors. SERPINA3 is located on human chromosome 14q32.1.
Application
Biochem/physiol Actions
Specific inhibitor of chymotrypsin-like serine proteases.
Specific inhibitor of chymotrypsin-like serine proteases. Promotes amyloid-β polymerization in vitro and in vivo. Levels in plasma and cerebrospinal fluid have been found to correlate with progression of dementia in Alzheimer′s patients and induce phosphorylation of tau protein in neurons.
α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G. It serves as a potential therapeutic target of endometrial carcinoma (EC).
Packaging
Package size based on protein content.
Physical form
Lyophilized powder containing Tris buffer salt and NaCl.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Dieser Artikel | |||
|---|---|---|---|
| description ≥92.5% (SDS-PAGE), lyophilized powder | description - | description ≥95% (SDS-PAGE) | description Acute-phase protein present at ~45 mg/100 ml in plasma. |
| biological source human plasma | biological source rabbit | biological source human | biological source - |
| assay ≥92.5% (SDS-PAGE) | assay - | assay ≥95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) |
| Gene Information human ... SERPINA3(12) | Gene Information human ... SERPINA3(12) | Gene Information human ... SERPINF2(5345) | Gene Information - |
| Quality Level 200 | Quality Level 100 | Quality Level - | Quality Level 100 |
| form lyophilized powder | form liquid | form lyophilized | form solid |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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