Fortfahren mit
B3056
Bisindolylmaleimide II
≥97% (Mixture of 2 isomers)
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 mg | Warenkorb auf Verfügbarkeit prüfen | € 140,00 |
Über diesen Artikel
biological source
synthetic (organic)
Quality Segment
assay
≥97% (Mixture of 2 isomers)
form
powder
solubility
DMSO: soluble, ethanol: soluble
shipped in
dry ice
storage temp.
−20°C
SMILES string
CN1CCCC1CCn2cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c6ccccc26
InChI
1S/C27H26N4O2/c1-30-13-6-7-17(30)12-14-31-16-21(19-9-3-5-11-23(19)31)25-24(26(32)29-27(25)33)20-15-28-22-10-4-2-8-18(20)22/h2-5,8-11,15-17,28H,6-7,12-14H2,1H3,(H,29,32,33)
InChI key
LBFDERUQORUFIN-UHFFFAOYSA-N
Application
- as a protein kinase C (PKC) inhibitor to study its effects on cardiomyocyte phenotypes
- as a PKC inhibitor along with methanandamide (mAEA) to study its effects on murine gastric vagal afferent (GVA) mechanosensitivity
- as a PKC/protein kinase A (PKA) inhibitor to study its effects on bone-marrow cells
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Dieser Artikel | ||
|---|---|---|
| description ≥97% (Mixture of 2 isomers) | description A highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor (IC50 = 10 nM) that is structurally similar to staurosporine. | description A potent, cell permeable, and selective inhibitor of protein kinase C (IC50 = 87 nM). |
| assay ≥97% (Mixture of 2 isomers) | assay ≥95% (HPLC) | assay ≥98% (TLC) |
| form powder | form solid | form powder, solid |
| Quality Level 200 | Quality Level 100 | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: soluble, ethanol: soluble | solubility DMSO: 10 mg/mL | solubility methanol: 10 mg/mL |
| shipped in dry ice | shipped in ambient | shipped in - |
Lagerklasse
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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