B3061

Borrelidin

From Streptomyces parvulus, ≥98% (HPLC), angiogenesis inhibitor, powder

• Synonym(e): 2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)-cyclopentanecarboxylic acid, Borrelidine, Cyclopentanecarboxylic acid, NSC 216128, Treponemycin
• Empirische Formel (Hill-System): C₂₈H₄₃NO₆
• CAS-Nummer: 7184-60-3
• Molekulargewicht: 489.64
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724417
• NACRES: NA.77
• MDL number: MFCD01740784
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Borrelidin, from Streptomyces parvulus, ≥98% (HPLC)
• biological source: Streptomyces parvulus
• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• solubility: DMSO: 1 mg/mL, methanol: 1 mg/mL
• antibiotic activity spectrum: viruses
• mode of action: enzyme | inhibits
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: [H][C@]1(CCC[C@H]1C(O)=O)[C@@H]2C\C=C\C=C(C#N)[C@H](O)[C@@H](C)C[C@H](C)C[C@H](C)C[C@H](C)[C@@H](O)CC(=O)O2
• InChI: 1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1
• InChI key: OJCKRNPLOZHAOU-UGKRXNSESA-N

Beschreibung

General description

Chemical structure: macrolide

Biochem/physiol Actions

Borrelidin is a potent angiogenesis inhibitor that induces apoptosis in capillary tube-forming cells. Also displays antimalarial activity against drug-resistant Plasmodia. Antimicrobial and selective threonyl t-RNA synthetase inhibitor.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)