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C1129

Cholinsäure

from bovine and/or ovine, ≥98%

Synonym(e):

3α,7α,12α-Trihydroxy-5β-cholansäure, Cholansäure

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Größe/SKUVerfügbarkeitPreis
25 g
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€ 74,10
100 g
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€ 180,00
500 g
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€ 520,00
1 kg
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€ 876,00

Über diesen Artikel

Empirische Formel (Hill-System):
C24H40O5
CAS-Nummer:
Molekulargewicht:
408.57
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
EC Number:
201-337-8
Beilstein/REAXYS Number:
2822009
MDL number:

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biological source

bovine and/or ovine

Quality Segment

description

anionic

assay

≥98%

form

powder

mol wt

408.57 g/mol

mp

200-201 °C (lit.)

solubility

water: soluble 0.175 g/L at 25 °C

application(s)

pharmaceutical

functional group

carboxylic acid

shipped in

ambient

storage temp.

room temp

SMILES string

[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(O)=O

InChI

1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1

InChI key

BHQCQFFYRZLCQQ-OELDTZBJSA-N

Gene Information

human ... CYP1A2(1544)

General description

Cholic acid is a major primary bile acid produced in the liver which facilitates fat absorption and cholesterol excretion. It is a non-denaturing ionic detergent.

Application

Dietary cholic acid has been used in a study to assess its effect on colonic epithelial cell proliferation. It has also been used in a study to investigate extractions and comparisons of human erythrocyte ghosts.
Nicht-ionisches, nicht-denaturierendes Detergenz für die Extraktion von Membranproteinen

Biochem/physiol Actions

Gallensäure

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Dieser Artikel
1133503C9377D2510
description

from bovine and/or ovine, ≥98%

description

United States Pharmacopeia (USP) Reference Standard

description

-

description

≥98% (HPLC)

assay

≥98%

assay

-

assay

-

assay

≥98% (HPLC)

form

powder

form

-

form

powder

form

powder

application(s)

pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

storage temp.

room temp

storage temp.

-

storage temp.

room temp

storage temp.

room temp

biological source

bovine and/or ovine

biological source

-

biological source

-

biological source

bovine bile (ex gall bladder)

solubility

water: soluble 0.175 g/L at 25 °C

solubility

-

solubility

-

solubility

-


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Lagerklasse

11 - Combustible Solids

Was ist los?

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

PSA (Persönliche Schutzausrüstung)

Eyeshields, Gloves, type N95 (US)



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Questions

1–4 of 4 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Can the cholic acid be frozen once in solution?

    1 answer
    1. Unfortunately, the solution stability of this product has not been determined.

      Helpful?

  4. what is the solubility of cholic acid in DMSO, Ethanol or PBS?

    1 answer
    1. This product is tested for solubility in methanol at 50 mg/mL. Other possible solvents have not been evaluated.

      Helpful?

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