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C8788

Complement C3 deficient serum human

substrate serum for C3 activity

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Größe/SKUVerfügbarkeitPreis
1 mL
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€ 470,00

Über diesen Artikel

NACRES:
NA.32
UNSPSC Code:
12352200
Biological source:
human
Form:
solution
Shipped in:
dry ice

€ 470,00


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biological source

human

Quality Segment

form

solution

usage

substrate serum for C3 activity

technique(s)

activity assay: suitable

impurities

infectious agent, tested

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... C3(718)

General description

Complement C3 deficient serum is a normal human serum in which C3 protein is removed by affinity chromatography. Depleted serum helps in the complement cascade up to the preferred convertase level. It eases the formation of enzyme complex from purified components.

Application

Complement C3 deficient serum human has been used:
  • as a component of the culture medium to study the influence of the inhibition of complement activation on complement receptors (CR3 and C3aR) expression in CD3+CD56+NKT-like cells
  • as a negative control to evaluate the downstream complement activation post-mannan-binding lectin (MBL) pathway activation
  • to study the opsonization of foreign particles by complement system

Physical form

Supplied as a solution in phosphate buffered saline, pH 7.4

Analysis Note

C3 is depleted by immunoadsorption as judged by a highly sensitive hemolytic assay.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Dieser Artikel
C2910C8195C3535
description

substrate serum for C3 activity

description

≥3000 C3H50 units/mg (using C3 deficient serum)

description

≥300,000 C4H50 units/mg protein

description

suitable for radioiodination, RIA, ≥85% (SDS-PAGE), ≥125,000 C8H50 units/mg protein (using C8 deficient serum)

technique(s)

activity assay: suitable

technique(s)

activity assay: suitable

technique(s)

activity assay: suitable

technique(s)

immunoelectrophoresis: suitable

form

solution

form

solution

form

solution

form

solution

biological source

human

biological source

human

biological source

human serum

biological source

human

impurities

infectious agent, tested

impurities

-

impurities

-

impurities

-

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C


Lagerklasse

10 - Combustible liquids

Was ist los?

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable



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