DMS 92

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA.

• UNSPSC Code: 41106514
• Biological source: human lung (bone marrow metastasis)
• Relevant disease(s): metastasis
• Growth mode: Aggregates in suspension
• Karyotype: Modal no. 44
• Morphology: Not specified
• Manufacturer/tradename: ECACC

Eigenschaften

• biological source: human lung (bone marrow metastasis)
• manufacturer/tradename: ECACC
• packaging: tube of 5 μg 95062825-DNA-5UG, pkg of vial of cells 95062825-1VL
• growth mode: Aggregates in suspension
• karyotype: Modal no. 44
• morphology: Not specified
• products: Not specified
• receptors: Not specified
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): metastasis
• shipped in: dry ice
• storage temp.: −196°C

Beschreibung

Application

Human lung tumour model

Biochem/physiol Actions

DMS 92 was obtained from a bone marrow aspirate of an untreated 39 year old male at time of diagnosis. The isolated cells were identified as small cell carcinoma of the lung (SCLC). DMS 92 cells secrete adrenocorticotropin (ACTH), bombesin (BN), oxytocin-neurophysin (OT-NP) and 17 β-estradiol. Cells produce tumours in athymic nude mice.

Human Caucasian lung small cell carcinoma, metastasis to bone marrow

Preparation Note

Maintain cultures between 3-9x100,000 cells/ml; 5% CO₂; 37°C.

Waymouth′s MB 752/1 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) (Heat Inactivated).

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

This cell line is part of the European Collection of Authenticated Cell Cultures (ECACC), an international repository managed by the United Kingdom Health Security Agency (UKHSA). No licensing agreement is required when either this cell line or the DNA extracted from it are used for internal research purposes only. Any other use of these products is prohibited without the express written permission of UKHSA. Inquiries regarding authorized use of this cell line or its genomic DNA may be directed to culturecollections@ukhsa.gov.uk.