D2293

N-(2,4-Dinitrophenyl)-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg amide

• Empirische Formel (Hill-System): C₄₅H₆₄N₁₄O₁₁
• CAS-Nummer: 121282-17-5
• Molekulargewicht: 977.08
• UNSPSC Code: 12352204
• PubChem Substance ID: 24893676
• MDL number: MFCD00133551

Eigenschaften

• solubility: H₂O: 2 mg/mL
• storage temp.: −20°C
• SMILES string: CC(C)C[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1c2ccc(cc2N(=O)=O)N(=O)=O)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(=O)N[C@@H](C)C(=O)N[C@H](CCCNC(N)=N)C(N)=O

Beschreibung

General description

Fluorogenic substrate for matrix metalloproteinases (MMP-1 and MMP-9). The tryptophan fluorescence of the intact molecule is quenched by the dinitrophenyl moiety. Enzymatic cleavage of the substrate by collagenase or gelatinase results in an increased fluorescence.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)