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F0806
Factor IX human
aqueous glycerol solution, ≥145 units/mg protein
Synonym(e):
Christmas factor, Plasma thromboplastin component
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 100 μg | Warenkorb auf Verfügbarkeit prüfen | € 365,00 |
Über diesen Artikel
Form:
aqueous glycerol solution
Biological source:
human
Mol wt:
55 kDa
Technischer Dienst
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Unterstützung erhaltenGeneral description
Factor IX is a 55 kDa single chain vitamin K-dependent plasma zymogen which plays a key role in the intrinsic and extrinsic blood coagulation systems.
Application
Factor IX is plasma zymogen key to blood coagulation systems. It has been used in studies of portal vein thrombosis (PVT) in hepatocellular carcinoma (HCC). It has been found that abnormalities in factor IX contribute to PVT in HCC patients. Additionally, it has been used in studies of changes in the coagulation system in patients with inflammatory bowel disease (IBD).
Physical form
Aqueous solution containing 50% (v/v) glycerol
Other Notes
One unit is equivalent to the Factor IX activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C.
View this factors role in the Coagulation Cascade
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Dieser Artikel | |||
|---|---|---|---|
| technique(s) ligand binding assay: suitable | technique(s) ligand binding assay: suitable | technique(s) - | technique(s) - |
| biological source human | biological source human | biological source human plasma | biological source - |
| mol wt 55 kDa | mol wt - | mol wt - | mol wt - |
| form aqueous glycerol solution | form aqueous glycerol solution | form liquid | form liquid |
| specific activity ≥145 units/mg protein | specific activity ≥25 units/mg protein | specific activity ≥150 units/mg protein (clotting assay) | specific activity ≥20 units/mg protein |
| Gene Information human ... F9(2158) | Gene Information human ... F5(2153) | Gene Information - | Gene Information - |
Lagerklasse
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Verwandter Inhalt
Instructions
Uri Martinowitz et al.
Thrombosis research, 131 Suppl 2, S11-S14 (2013-03-30)
Recombinant fusion protein linking coagulation factor IX with albumin (rIX-FP) is a novel recombinant albumin fusion protein designed to extend the half-life of recombinant factor IX (rFIX), which is used in the management of hemophilia B. Clinical evaluation of rIX-FP
Brian R Branchford et al.
Current opinion in pediatrics, 25(1), 23-30 (2013-01-01)
Disorders of hemostasis such as hemophilia, von Willebrand disease (VWD), and other clotting protein deficiencies lead to significant morbidity in the pediatric population. Because of the limitations of current treatment options, novel therapies are being developed, many of which are
Hemostatic Abnormalities in Cirrhosis and Tumor-Related Portal Vein Thrombosis.
Alkim H., et al.
Clinical and Applied Thrombosis/Hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis (2011)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| F0806-100UG | 04061838031044 |