F5804

Anti-FBG3 (FBXO44) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-F Box 3
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD08705455
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 4

Eigenschaften

• biological source: rabbit
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~30 kDa by calculation
• species reactivity: human
• technique(s): western blot: 1:500-1:1,000
• UniProt accession no.: Q9H4M3
• shipped in: dry ice
• storage temp.: −20°C
• Gene Information: human ... FBXO44(93611) ; mouse ... Fbxo44(230903) ; rat ... Fbxo44(500587)

Beschreibung

Immunogen

peptide corresponding to the human FBG3 protein (amino acids 103-119). This sequence has 94% homology with mouse and rat.

Application

Anti-FBG3 (FBXO44) antibody is suitable for western blot: 1:500-1:1,000.

Biochem/physiol Actions

F-box protein, is the critical component of conserved ubiquitin–protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box) and acts as a substrate recognition component of the ubiquitin ligase complex SCF (Skp-Cullin-F-box). It is expressed in human tissues including kidney, liver, brain and muscle tissues. It is associated with various critical biological processes such as in regulating the cell cycle, immune response, signaling cascades and developmental programs. The proteins have a bipartite structure and the core complex, whereas divergent protein-protein interaction motifs selectively bind their cognate substrates.

Physical form

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable