F7016

Flumequin

≥97.0% (HPLC)

• Synonym(e): 9-Fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid
• Empirische Formel (Hill-System): C₁₄H₁₂FNO₃
• CAS-Nummer: 42835-25-6
• Molekulargewicht: 261.25
• UNSPSC Code: 51102829
• NACRES: NA.85
• PubChem Substance ID: 24894926
• EC Number: 255-962-6
• Beilstein/REAXYS Number: 490724
• MDL number: MFCD00079298

Eigenschaften

• assay: ≥97.0% (HPLC)
• form: powder
• color: white to off-white
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: DNA synthesis | interferes, enzyme | inhibits
• SMILES string: CC1CCc2cc(F)cc3C(=O)C(=CN1c23)C(O)=O
• InChI: 1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)
• InChI key: DPSPPJIUMHPXMA-UHFFFAOYSA-N

Beschreibung

General description

Chemical structure: fluoroquinolone

Biochem/physiol Actions

Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited .

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)