F8527

Monoclonal Anti-CD45−FITC/CD14-PE DUAL-TAG^™ antibody produced in mouse

clone BRA-55/UCHM-1, purified immunoglobulin, buffered aqueous solution

• UNSPSC Code: 12352203
• MDL number: MFCD00213147

Eigenschaften

• biological source: mouse
• conjugate: FITC conjugate, phycoerythrin (R-PE) conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: BRA-55/UCHM-1, monoclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): flow cytometry: 20 μL using 1 × 10⁶ cells
• isotype: IgG1/IgG2a
• UniProt accession no.: P08571
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: human ... CD14(929), PTPRC(5788)

Beschreibung

Application

Monoclonal Anti-CD45-FITC/CD14-PE DUAL-TAG^™ antibody is suitable for flow cytometry at a concentration of 20μL using 1×106 cells.

Biochem/physiol Actions

CD45 is a family of single chain transmembrane glycoproteins, consisting of different isoforms, which share a common large intracellular domain. It is abundantly present in leukocyte cell surface and belongs to a novel class of enzymes, the protein tyrosine phosphatases (PTPs). It plays an essential role in thymic selection and peripheral activation of T and B cells. It is associated with various signal transduction pathways. It may also accelerate the Src family tyrosine kinases activity. an important determinant of immune tolerance.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Legal Information

DUAL-TAG is a trademark of Sigma-Aldrich Co. LLC

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.