L119

L-703,606 oxalate salt hydrate

NK-1 tachykinin receptor antagonist, solid

• Synonym(e): cis-2-(Diphenylmethyl)-N-[(2-iodophenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine oxalate salt
• Empirische Formel (Hill-System): C₂₇H₂₉IN₂ · C₂H₂O₄ · xH₂O
• CAS-Nummer: 351351-06-9
• Molekulargewicht: 598.47 (anhydrous basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278100
• NACRES: NA.77
• MDL number: MFCD11045930
• Form: solid
• Storage condition: desiccated

Eigenschaften

• Produktname: L-703,606 oxalate salt hydrate, solid
• form: solid
• Quality Segment: 100
• storage condition: desiccated
• color: white
• solubility: DMSO: >10 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 11 mg/mL, H₂O: slightly soluble <2 mg/mL
• SMILES string: O.OC(=O)C(O)=O.Ic1ccccc1CN[C@@H]2C3CCN(CC3)[C@@H]2C(c4ccccc4)c5ccccc5
• InChI: 1S/C27H29IN2.C2H2O4.H2O/c28-24-14-8-7-13-23(24)19-29-26-22-15-17-30(18-16-22)27(26)25(20-9-3-1-4-10-20)21-11-5-2-6-12-21;3-1(4)2(5)6;/h1-14,22,25-27,29H,15-19H2;(H,3,4)(H,5,6);1H2/t26-,27-;;/m1../s1
• InChI key: NJAUFRHNYIJKDW-AJUXDCMMSA-N
• Gene Information: human ... TACR1(6869)

Beschreibung

Biochem/physiol Actions

Potent and selective non-peptide NK-1 tachykinin receptor antagonist.

Disclaimer

Hygroscopic

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)