L131

L-745,870 hydrochloride

• Synonym(e): 3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine hydrochloride
• Empirische Formel (Hill-System): C₁₈H₁₉ClN₄ · HCl
• CAS-Nummer: 1173023-36-3
• Molekulargewicht: 363.28
• NACRES: NA.77
• PubChem Substance ID: 24277918
• UNSPSC Code: 12352200
• MDL number: MFCD01529971
• Form: solid

Eigenschaften

• form: solid
• Quality Segment: 100
• color: white
• solubility: H₂O: 0.2 mg/mL, ethanol: 1.4 mg/mL, 0.1 M HCl: 5.5 mg/mL
• SMILES string: Cl.Clc1ccc(cc1)N2CCN(CC2)Cc3c[nH]c4ncccc34
• InChI: 1S/C18H19ClN4.ClH/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18;/h1-7,12H,8-11,13H2,(H,20,21);1H
• InChI key: GFFJYISJZJIKAF-UHFFFAOYSA-N
• Gene Information: human ... DRD4(1815)

Beschreibung

Biochem/physiol Actions

Selective D₄ dopamine receptor antagonist.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Manufactured and sold under license from Merck & Co., Inc., Kenilworth, NJ, U.S. for use solely for preclinical researchy purposes (i.e., not for the administration to or other use in humans).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)