L7016

Monoclonal Anti-LDH (H-Subunit) antibody produced in mouse

clone HH-17, ascites fluid

• Synonym(e): Anti-Lactic Dehydrogenase (H-Subunit)
• UNSPSC Code: 12352203
• NACRES: NA.46
• MDL number: MFCD00164663
• Conjugate: unconjugated
• Clone: HH-17, monoclonal
• Application: ELISA (i)
• Citations: 11

Eigenschaften

• biological source: mouse
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: HH-17, monoclonal
• contains: 15 mM sodium azide
• species reactivity: human
• technique(s): indirect ELISA: 1:5,000
• isotype: IgG1
• UniProt accession no.: P07195
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... LDHB(3945)

Beschreibung

General description

Lactate dehydrogenase (LDH) is an NADH-dependent enzyme that catalyzes the reversible conversion of pyruvate to lactate. Human LDH has two known isoforms, the H isoform which is primarily found in heart tissues and the M isoform that occurs mostly in muscle tissues.

Monoclonal Anti-LDH (H-Subunit) (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.

Immunogen

Human LDH-H4 isoenzyme

Application

Monoclonal Anti-LDH (H-Subunit) antibody produced in mouse has been used in:

• immunoblotting†
• immunohistochemistry
• microscopy

Biochem/physiol Actions

Lactate dehydrogenase (LDH) is an NADH-dependent enzyme that catalyzes the reversible conversion of pyruvate to lactate.

Lactate dehydrogenase (LDH) is an NADH-dependent enzyme that catalyzes the reversible conversion of pyruvate to lactate. Human LDH has two known isoforms, the H isoform which is primarily found in heart tissues and the M isoform that occurs mostly in muscle tissues . Ratio of LDH isozymes H4 and H3M can be used as diagnostic and prognostic markers of myocardial infarction . Monoclonal Anti-Human Lactate Dehydrogenase is specific for human LDH isozymes containing the H-subunit. The antibody does not cross-react with the M4 isozyme.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
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