If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
50 g | Warenkorb auf Verfügbarkeit prüfen | € 222,00 |
250 g | Warenkorb auf Verfügbarkeit prüfen | € 821,00 |
1 kg | Warenkorb auf Verfügbarkeit prüfen | € 2.470,00 |
Über diesen Artikel
Quality Segment
assay
≥99% (titration)
form
powder
storage condition
dry at room temperature
impurities
≤1.0% water
color
white
pH
2.5-4 (25 °C, 97.6 g/L)
useful pH range
5.5-6.7
pKa
6.1
density
1.23 g/cm3 at 20—25 °C, 1.27 g/cm3 at 20—25 °C
application(s)
clinical research
diagnostic assay manufacturing
life science and biopharma (
)
metabolomics (
)
SMILES string
OS(=O)(=O)CCN1CCOCC1
InChI
1S/C6H13NO4S/c8-12(9,10)6-3-7-1-4-11-5-2-7/h1-6H2,(H,8,9,10)
InChI key
SXGZJKUKBWWHRA-UHFFFAOYSA-N
General description
Dieser vielseitige Puffer wird auf verschiedene Weise bei der Aufrechterhaltung einer stabilen Umgebung in Lösungen für Zellkulturmedien, proteinbasierten Pufferformulierungen und Elektrophorese-Laufpuffern eingesetzt. Es eignet sich außerdem für die Aufreinigung von Antikörpern, Peptiden, Proteinen, Blutbestandteilen und Wachstumsfaktoren. Dank seiner geringen Ionenmobilität ist der MES-Puffer zudem eine hervorragende Wahl für die Kapillarelektrochromatografie. Er bietet insbesondere eine sicherere Alternative zu potenziell giftigen Substanzen wie Cacodylat oder nicht-zwitterionischen Puffern wie Citrat und Malat. MES-Puffer dient außerdem hervorragend dazu, den pH-Wert von Nährmedien einzustellen und enzymatische Lösungen zu stabilisieren, sowie als Bestandteil von PAGE-Laufpuffern für verschiedene Experimente.
Application
Features and Benefits
- Bestätigte geringe Schwermetallkontamination, geeignet für verschiedene Anwendungen
- Effektive Pufferung von pH 5,5 bis 6,7 mit einem pKa-Wert von 6,1 (25 °C)
- Hohe Löslichkeit in Wasser
- Minimale Bindung an Metallionen
- Weniger toxisch für Zellen als andere Puffer wie Tris und Phosphat
- Stabil in einem breiten pH-Bereich
- Geringe UV-Absorptionsfähigkeit und minimale Reaktivität
Analysis Note
Other Notes
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description low moisture content, ≥99% (titration) | description BioUltra, Molecular Biology, 0.5 M in H2O | description ≥99.5% (titration) | description BioXtra, ≥99.0% (T) |
| assay ≥99% (titration) | assay - | assay ≥99.5% (titration) | assay ≥99.0% (T) |
| Quality Level 400 | Quality Level 200 | Quality Level 400 | Quality Level 200 |
| application(s) clinical research | application(s) - | application(s) agriculture | application(s) agriculture |
| form powder | form liquid | form crystalline powder | form powder or crystals |
| density 1.23 g/cm3 at 20—25 °C, 1.27 g/cm3 at 20—25 °C | density - | density - | density - |
| pH 2.5-4 (25 °C, 97.6 g/L) | pH 2.5-4.0 (25 °C in neat) | pH - | pH - |
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Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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How can I determine the shelf life / expiration / retest date of this product?
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Helpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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What is the solubility of Product M3671, MES - low moisture?
1 answer-
We test the solubility of Prod. No. M3671 at 20 grams in 80 mL of water. A clear, colorless solution is obtained. This concentration is not necessarily the upper solubility limit of MES in water.
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How does one prepare a buffer using Product M3671, MES - low moisture, free acid?
1 answer-
A buffer using MES free acid can be prepared by titrating the free acid with sodium hydroxide to the desired pH. Alternatively, volumes of equimolar MES free acid and sodium MES can be mixed to attain the desired pH.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What does low moisture content mean in the description of Product M3671, MES - low moisture?
1 answer-
The amount of water/moisture for MES (M3671) is tested by Karl Fisher and meets a specification of less than 1%. The other MES Hydrates offered have a specification of less than 9%.
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Is Product M3671, MES - low moisture, autoclavable?
1 answer-
Autoclaving is not recommended for any sulfonic acid buffer solution. Sterilization of a MES buffer solution can be accomplished by filtering it through a 0.2 micron filter.
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What is the pH of a solution of Product M3671, MES - low moisture?
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The pH of a 0.5 M solution in water should be between 2.5 and 4.0.
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