M5696

Myoglobin aus Pferdeskelettmuskel

BioUltra, 95-100% (SDS-PAGE)

• Synonym(e): Myoglobin aus Pferdeskelettmuskel
• CAS-Nummer: 100684-32-0
• UNSPSC Code: 12352202
• EC Number: 309-705-0
• NACRES: NA.61
• MDL number: MFCD00131643
• Form: essentially salt-free, lyophilized powder
• Assay: 95-100% (SDS-PAGE)
• Biological source: equine skeletal muscle
• Mol wt: ~17 kDa(lit.)

Eigenschaften

• biological source: equine skeletal muscle
• product line: BioUltra
• assay: 95-100% (SDS-PAGE)
• form: essentially salt-free, lyophilized powder
• mol wt: ~17 kDa(lit.)
• purified by: affinity chromatography
• Iron content content: ~0.30%
• technique(s): mass spectrometry (MS): suitable
• solubility: H₂O: soluble 10 mg/mL
• UniProt accession no.: P68082
• storage temp.: −20°C
• Gene Information: horse ... MB(100054434)

Beschreibung

Application

Myoglobin from equine skeletal muscle has been used to induce acute kidney injury (AKI) in mice. It has also been used as a standard for top down mass spectrometry.

Myoglobin is used as a molecular weight marker and a standard for mass spectroscopy and X-ray crystallography.Myoglobin from equine skeletal muscle was used in a study to test experimental protein mixture for validating tandem mass spectral analysis.

Biochem/physiol Actions

Myoglobin from horse skeletal muscle is a single chain heme protein containing 153 amino acid residues. It possesses no disulfide bridges or free -SH groups. Myoglobin contains 8 variously sized right-handed helical regions, joined by non-ordered or random coil regions.
Myoglobin is critical to skeletal muscle O₂ supply at near-maximum oxygen demand, and prevents anoxia by maintaining PO₂ above levels needed to support mitochondrial function.

Myoglobin ist für die O₂-Versorgung der Skelettmuskulatur bei nahezu maximalem Sauerstoffbedarf von entscheidender Bedeutung; es hält den PO₂-Gehalt über dem für die Funktion der Mitochondrien erforderlichen Wert und verhindert so Sauerstoffmangel (Anoxie).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)