M7195

Anti-MO25 (C-terminus) in Kaninchen hergestellte Antikörper

~2 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-CAB39, Anti-CGI-66, Anti-Calcium binding protein 39
• NACRES: NA.44
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 2

Eigenschaften

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen ~40 kDa
• species reactivity: human, mouse (predicted), rat (predicted)
• packaging: antibody small pack of 25 μL
• enhanced validation: recombinant expression; Learn more about Antibody Enhanced Validation
• concentration: ~2 mg/mL
• technique(s): western blot: 0.5-1 μg/mL using HEK-293T cells expressing human MO25 and PC12 cell lysates
• UniProt accession no.: Q9Y376
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CAB39(51719) ; mouse ... Cab39(12283) ; rat ... Cab39(301574)

Beschreibung

General description

MO25 is a 40 kDa scaffolding protein that interacts with STRADα and LKB1 to regulate tumor suppression. MO25 also facilitates the activation and cytoplasmic localization of LKB1 . Anti-MO25 (C-terminus) antibody detects human MO25 (approx. 40 kDa). The product is also predicted to react with rat and mouse MO25. Staining of the MO25 band in immunoblotting is specifically inhibited by the immunizing peptide.

Immunogen

synthetic peptide corresponding to amino acids 323-341 located near the C-terminus of human MO25. This sequence is identical in chicken, dog, and bovine MO25 and highly conserved in rat and mouse MO25 (2 amino acid substitutions).

Application

Anti-MO25 (C-terminus) antibody is suitable for use in western blot (0.5-1 μg/mL using HEK-293T cells expressing human MO25 and in PC12 cell lysates).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.