N8784

Norcantharidin

solid

• Empirische Formel (Hill-System): C₈H₈O₄
• CAS-Nummer: 29745-04-8
• Molekulargewicht: 168.15
• NACRES: NA.77
• PubChem Substance ID: 24278599
• UNSPSC Code: 12352202
• MDL number: MFCD00213361
• Form: solid

Eigenschaften

• form: solid
• SMILES string: O=C1OC(=O)C2C3CCC(O3)C12
• InChI: 1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2
• InChI key: JAABVEXCGCXWRR-UHFFFAOYSA-N
• Gene Information: human ... PPP2R5A(5525)

Beschreibung

General description

Norcantharidin (NCTD) is a demethylated derivative of cantharidin (CTD).

Application

Norcantharidin has been used in primary cell culture and treatment. It has also been used to treat mice inoculated with Huh7 cells subcutaneously.

Biochem/physiol Actions

Norcantharidin is a potential antitumor agent. Norcantharidin helps to block SK-N-SH neuroblastoma cell growth by stimulating autophagy and apoptosis.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)