The specific formulation of this product is considered proprietary. The Ready Made solution is prepared in water with undisclosed solubilizing agents.
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N9150
Nystatin
ready made solution, suitable for cell culture
Synonym(e):
Fungicidin, Mycostatin
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
20 mL | Warenkorb auf Verfügbarkeit prüfen | € 52,30 |
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Technischer Dienst
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Unterstützung erhaltenProduktname
Nystatin, suitable for cell culture
biological source
Streptomyces noursei
form
solution
technique(s)
cell culture | mammalian: suitable
shipped in
dry ice
storage temp.
−20°C
SMILES string
O[C@@H]([C@H](C)[C@H](C)O1)[C@@H](C)/C=C/C=C/CC/C=C/C=C/C=C/C=C/[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@]3([H])[C@H](C(O)=O)[C@@H](O)C[C@](O)(O3)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)C[C@@H](O)CC1=O
InChI
1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
InChI key
VQOXZBDYSJBXMA-QEKUPDCNSA-N
General description
Nystatin is a fungistatic and fungicidal polyene antibiotic. It binds to ergosterol which increases cell membrane permeability in sensitive fungi. Nystatin is mainly clinically active against Candida species. However, it is also reported to be effective against Aspergillus, Coccidioides immitis, Cryptococcus neoformans, Histoplasma capsulatum, Blastomyces dermatidis, and other yeasts and fungi. Nystatin has also been used to enrich mutants by negative selection in yeasts. The minimum inhibitory concentration (MIC) of Nystatin to Saccharomyces cerevisiae was reported to be 3μg/ml while for clinical isolates of Candida albicans the MIC was reported to be 4-16μg/ml.
Biochem/physiol Actions
Wirkungsweise: Erhöht die Permeabilität der Zellmembran von empfindlichen Pilzen durch Bindung an Sterole.
Antimikrobielles Spektrum: Hefen und Schimmelpilze.
Antimikrobielles Spektrum: Hefen und Schimmelpilze.
Features and Benefits
- Nystatin ready made solution is a fully solubilized formulation of Nystatin with potency of 8000-13000 units/ml according to USP standard.
- Nystatin ready made solution is 0.2μm filtered, endotoxin.
- The suggested working concentration of Nystatin ready made solution is 30 units/ml.
- The ready made solution is light sensitive. It is recommended to store the solution in the dark.
- It is recommended to avoid freeze thaw cycles of this product. Therefore, it is recommended to aliquot and store at -20°C.
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Dieser Artikel | |||
|---|---|---|---|
| description suitable for cell culture | description suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture | description ≥4,400 units/mg | description United States Pharmacopeia (USP) Reference Standard |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) - |
| form solution | form suspension | form powder | form solid |
| biological source Streptomyces noursei | biological source - | biological source - | biological source - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. - |
| shipped in dry ice | shipped in dry ice | shipped in - | shipped in - |
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Lagerklasse
12 - Non Combustible Liquids
Was ist los?
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Hi, can you please let us know in which solvant the "Nystatin ready made solution, suitable for cell culture" is prepare so we can prepare the appropriate control ?
1 answer-
Helpful?
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N9150 Nystatin Lot番号0000275117の濃度 mMを教えて頂けないでしょうか？11243 units /mlとしかわからず困っています。
1 answer-
This product is prepared according to the lot-specific activity of the starting material. A molar concentration is not available. Should this be required, consider preparing a suspension from a powder product option. The molecular weight of Nystatin is reported as 926.09 g/mol. Please see the link below to review powder product options:
https://www.sigmaaldrich.com/search/nystatin?facet=facet_physical_form%3Apowder&focus=products&page=1&perpage=30&sort=relevance&term=nystatin&type=productHelpful?
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