Fortfahren mit
P215
PD 98,059
MAPKK inhibitor, solid
Synonym(e):
2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one, PD98059
Größe auswählen
| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 172,00 |
1 mg | Warenkorb auf Verfügbarkeit prüfen | € 203,00 |
Über diesen Artikel
Produktname
PD 98,059, solid
form
solid
Quality Segment
color
yellow
solubility
DMSO: 10 mg/mL, clear
storage temp.
−20°C
SMILES string
COc1cccc(c1N)C2=CC(=O)c3ccccc3O2
InChI
1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3
InChI key
QFWCYNPOPKQOKV-UHFFFAOYSA-N
Gene Information
Application
- in growth medium as a mitogen-activated protein (MAP) kinase inhibitor, in order to study the secondary messengers involved in the effect of D1-like receptors
- in calcium-free RPMI (Roswell park memorial institute)-1640 medium to study its effect on inflammation, proliferation and differentiation in human epidermal keratinocyte cell line in conjunction of cystic fibrosis transmembrane conductance regulator (CFTR) knockdown
- in culture medium for cell migration assay
Biochem/physiol Actions
Features and Benefits
Legal Information
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Dieser Artikel | |||
|---|---|---|---|
| description solid | description PD 98059, CAS 167869-21-8, is a cell-permeable, selective & reversible inhibitor of MAP Kinase Kinase (MEK). Inhibits MAP Kinase activation and subsequent phosphorylation of MAP Kinase substrates. | description InSolution, ≥98%, 5 mg/ml, reversible inhibitor of MAP Kinase Kinase (MEK) | description targeting human MAP2K6 |
| form solid | form solid | form liquid | form lyophilized, lyophilized powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| solubility DMSO: 10 mg/mL, clear | solubility methanol: 0.7 mg/mL, DMSO: 20 mg/mL | solubility - | solubility - |
| color yellow | color pale yellow | color - | color - |
| Gene Information human ... MAP2K1(5604), MAP2K2(5605), MAP2K3(5606), MAP2K4(6416), MAP2K5(5607), MAP2K6(5608), MAP2K7(5609), MAP3K1(4214), RAF1(5894) | Gene Information - | Gene Information - | Gene Information human ... MAP2K6(5608) |
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Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
PSA (Persönliche Schutzausrüstung)
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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