P222

Pandinotoxin-Kα

>99%, powder

• Empirische Formel (Hill-System): C₁₆₉H₂₆₇N₅₃O₄₈S₇
• CAS-Nummer: 185529-64-0
• Molekulargewicht: 4033.71
• UNSPSC Code: 12352200
• NACRES: NA.32
• MDL number: MFCD01324942

Eigenschaften

• assay: >99%
• form: powder
• color: off-white
• storage temp.: −20°C

Beschreibung

General description

Pandinotoxin (PiTX)-Kα is a 35 amino acid peptide isolated from venom of the scorpion Pandinus imperaton. PiTX-Kβ and PiTXγ are other two members of pandinotoxin group. All the three pandinotoxins have structures similar to another scorpion toxin charybdotoxin (ChTX). The structure of PiTXs contains a β-sheet at the C- terminal end with three cysteines which is linked to the central α-helix by two disulfide bridges (C17-C35 and C13-C33) and to an extended amino-terminal fragment by the third disulfide bridge (C7-C28).

Biochem/physiol Actions

Pandinotoxin (PiTX) –Kα along with PiTX-Kβ and PiTXγ plays a vital role in blocking voltage-gated K⁺ channels.

Legal Information

Sold with the permission of University of Maryland.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)