P3496

(+/-)-8-Prenylnaringenin

EGF signaling inhibitor, powder

• Empirische Formel (Hill-System): C₂₀H₂₀O₅
• Molekulargewicht: 340.37
• UNSPSC Code: 12352200
• PubChem Substance ID: 329820176
• NACRES: NA.56
• MDL number: MFCD00272175
• Form: powder

Eigenschaften

• Produktname: (+/-)-8-Prenylnaringenin, Plant-derived estrogen receptor ligand
• Quality Segment: 200
• form: powder
• storage temp.: −20°C
• SMILES string: C\C(C)=C\Cc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccc(O)cc3
• InChI: 1S/C20H20O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9,18,21-23H,8,10H2,1-2H3
• InChI key: LPEPZZAVFJPLNZ-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

8-Prenylnaringenin, a strong plant-derived estrogen receptor ligand, is a phytoestrogen that inhibits multidrug resistance-associated transporters, P-glycoprotein and MRP1. 8-Prenylnaringenin also inhibits EGF signaling at the level of phosphatidylinositol-3-OH kinase ((PI(3)K))activity.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)