The stability of this compound in solution has not been determined. However, various sources recommend that solutions not be stored for more than 1 day. If necessary, stock solutions may be stored in aliquots at -20°C for up to 1 month. This information has not been validated.
Fortfahren mit
P4620
PD 146176
≥98% (HPLC), solid
Synonym(e):
6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 180,00 |
25 mg | Warenkorb auf Verfügbarkeit prüfen | € 635,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C15H11NS
CAS-Nummer:
Molekulargewicht:
237.32
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Technischer Dienst
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Unterstützung erhaltenQuality Segment
assay
≥98% (HPLC)
form
solid
color
white to beige
solubility
DMSO: soluble >10 mg/mL, H2O: insoluble
SMILES string
C1Sc2ccccc2-c3[nH]c4ccccc4c13
InChI
1S/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2
InChI key
ZGOOPZVQMLHPFM-UHFFFAOYSA-N
Gene Information
human ... ALOX15(246)
mouse ... ALOX15(11687)
rat ... ALOX15(81639)
Application
PD 146176 has been used to study its influence on ex vivo leukotriene B4 (LTB4) and lipoxin A4 (LXA4) secretion in adipose tissue.
Biochem/physiol Actions
15-Lipoxygenase inhibitor
PD 146176 blocks neuroprotectin D1 (NPD1) and eicosanoid synthesis by inhibiting the 5-lipoxygenase-1 (15-LOX-1) enzyme.
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Dieser Artikel | |||
|---|---|---|---|
| description ≥98% (HPLC), solid | description recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE) | description purified immunoglobulin, buffered aqueous solution | description Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution |
| assay ≥98% (HPLC) | assay ≥60% (SDS-PAGE) | assay - | assay - |
| form solid | form aqueous solution | form buffered aqueous solution | form buffered aqueous glycerol solution |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| solubility H2O: insoluble, DMSO: soluble >10 mg/mL | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
| Gene Information human ... ALOX15(246) | Gene Information human ... ALOX15(246) | Gene Information human ... ALOX15(246) | Gene Information human ... ALOX15(246) |
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
PSA (Persönliche Schutzausrüstung)
Eyeshields, Gloves, type N95 (US)
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