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P5660

3-sn-Phosphatidyl-L-serin Natriumsalz aus Rinderhirn

≥95% (TLC), Procoagulant and Hemostatic regulator, powder

Synonym(e):

1,2-Diacyl-sn-glycero-3-phospho-L-serine, L-α-Phosphatidyl-L-serine sodium salt

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Größe/SKUVerfügbarkeitPreis
5 mg
Warenkorb auf Verfügbarkeit prüfen
€ 419,00
25 mg
Warenkorb auf Verfügbarkeit prüfen
€ 1.670,00
100 mg
Warenkorb auf Verfügbarkeit prüfen
€ 4.300,00

Über diesen Artikel

UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥95% (TLC)
Form:
powder

€ 419,00


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Produktname

3-sn-Phosphatidyl-L-serin Natriumsalz aus Rinderhirn, ≥95% (TLC)

Quality Segment

assay

≥95% (TLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1

InChI key

SJRBMGBLPUBGJL-MBAWARMDSA-M

General description

Phosphatidylserine is an anionic phospholipid, which is found on the plasma membrane. Exposure of phosphatidylserine on the surface of plasma membrane stimulates the removal of apoptotic and red blood cells. It regulates the production of thrombin and maintains hemostasis.

Application

3-sn-Phosphatidyl-L-serine sodium salt from bovine brain has been used as a glycosylphosphatidylinositol (GPI)-anchor control.

Biochem/physiol Actions

A slowly metabolized structural phospholipid found mainly in gray matter.

Preparation Note

Washed with EDTA and converted to a sodium salt.

Disclaimer

Solutions exposed to room temperature will decompose about 0.5% per day.

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Dieser Artikel
P7769P6641P1185
description

≥95% (TLC)

description

≥97% (TLC), from bovine brain, amorphous powder

description

≥97%, from bovine brain, chloroform:methanol solution

description

≥99% (TLC)

assay

≥95% (TLC)

assay

≥97% (TLC)

assay

≥97%

assay

≥99% (TLC)

form

powder

form

amorphous powder

form

chloroform:methanol solution

form

powder

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


Lagerklasse

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

PSA (Persönliche Schutzausrüstung)

Eyeshields, Gloves, type N95 (US)



Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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Questions

1–7 of 7 Questions  
  1. Do you have any inhibitors for Protein Kinase C (PKC)?

    1 answer
    1. Yes. Two examples are Product No. C6303 (Calphostin C from Cladosporium cladosporioides) and Product No. C2932 (Chelerythrine chloride).

      Helpful?

  2. What is Product P5660, 3-sn-Phosphatidyl-L-serine sodium salt from bovine brain, soluble in?

    1 answer
    1. This product is soluble in chloroform:methanol (95:5 v/v) at a concentration of 50 mg/mL. It will likely form a suspension or emulsion in deionized water at a concentration of 1 mg/mL or higher.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. What is the solution stability of Product P5660, 3-sn-Phosphatidyl-L-serine sodium salt from bovine brain?

    1 answer
    1. Solutions can be divided into aliquots and stored at -20 °C. We have no information as to how long the solutions will be stable. Solution stability is enhanced when the compound is protected from oxygen, because the unsaturated fatty acids are subject to oxidation. To protect from oxidation, dissolve the compound in solvents in which oxygen has been removed and replaced with an inert gas such as nitrogen or argon.

      Helpful?

  5. What is the molecular weight of Product P5660, 3-sn-Phosphatidyl-L-serine sodium salt from bovine brain?

    1 answer
    1. The molecular weight of this compound is approximately 812.1 g/mole. This molecular weight assumes that stearoyl and oleoyl are the prodimant fatty acids in the compound.  Phosphatidylserine may have a number of different fatty acid residues associated with it.  Our analyses of multiple lots of phosphatidylserine identified average fatty acid percentages of approximately 40% for stearic acid and 30% for oleic acid.

      Helpful?

  6. Is 3-sn-Phosphatidyl-L-serine sodium salt from bovine brain available in solution?

    1 answer
    1. Yes. Product No. P6641 is a ready-to-use solution of phosphatidylserine in a chloroform:methanol mixture.

      Helpful?

  7. What is Product P5660, 3-sn-Phosphatidyl-L-serine sodium salt, commonly used for?

    1 answer
    1. Phosphatidylserine is important in enzymatic assays of purified protein kinase C. During activation of this enzyme, as part of the signal transduction process, phosphatidylserine, which is located on the inside of cellular plasma membranes, binds to cysteine residue domains on protein kinase C. Phosphatidylserine can be used as a standard in thin-layer chromatography and for artificial membrane studies such as in lipsome research.

      Helpful?

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