PLA0304

Goat anti-HIF1-alpha Antibody, Affinity Purified

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• Synonym(e): ARNT interacting protein, ARNT-interacting protein, HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PAS domain-containing protein 8, PASD8, alpha subunit (basic helix-loop-helix transcription factor), bHLHe78, basic-helix-loop-helix-PAS protein MOP1, class E basic helix-loop-helix protein 78, hypoxia inducible factor 1, hypoxia-inducible factor 1, hypoxia-inducible factor 1 alpha isoform I.3, hypoxia-inducible factor1alpha, member of PAS protein 1, member of PAS superfamily 1
• NACRES: NA.41
• UNSPSC Code: 12352203

Eigenschaften

• biological source: goat
• Quality Segment: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): immunoprecipitation (IP): 2- 10 μg/mg
• accession no.: NP_001521.1
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: goat ... HIF1-alpha(3091)

Beschreibung

Immunogen

The epitope recognized by PLA0304 maps to a region between residue 776 and 826 of human Hypoxia-Inducible Factor 1, Alpha Subunit using the numbering given in entry NP_001521.1 (GeneID 3091).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Hypoxia-inducible factor-1 (HIF1) is a basic helix-loop-helix (bHLH)-PER-ARNT-sim (PAS) transcription factor that plays a role in the cellular response to hypoxia. HIF1 is a heterodimer of an HIF1-alpha and HIF1-beta subunit. During normoxia, HIF-1alpha is regulated by ubiquitination and interaction with the von-Hippel-Lindau tumor suppressor protein (pVHL).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable