RB354-05

Rabbit Aortic Smooth Muscle Cells: RbAOSMC (Cryovial)

• NACRES: NA.81
• UNSPSC Code: 41106514
• eCl@ss: 32040201
• Biological source: rabbit aorta (normal tunica intima and media)
• Growth mode: Adherent
• Morphology: smooth muscle
• Relevant disease(s): cardiovascular diseases

Eigenschaften

• biological source: rabbit aorta (normal tunica intima and media)
• packaging: pkg of 500,000 cells
• manufacturer/tradename: Cell Applications, Inc
• growth mode: Adherent
• karyotype: 2n = 44
• morphology: smooth muscle
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): cardiovascular diseases
• shipped in: dry ice
• storage temp.: −196°C

Beschreibung

General description

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RbAOSMC from Cell Applications, Inc. were used to demonstrate that anti-restenosis drug probucol inhibition of vascular smooth cell proliferation by enhancing apoptosis and inducing heme oxygenase-1 (Deng, 2004). RbAOSMC were also used to evaluate performance of a novel pH/CO2 sensor system for measuring metabolic activity of cultured cells (Mohri, 2006); and to characterize the receptor pharmacology, antiplatelet activity, and vascular pharmacology of APD791, a novel 5-HT2A receptor antagonist (Adams, 2009).Characterization: positive for smooth muscle cell specific alpha-actin expression.

Application

aortic wall contraction, role of smc under normal conditions, blood pressure, distribution of oxygenated blood through systemic circulation

Biochem/physiol Actions

Aorta

Preparation Note

• 2nd passage, >500,000 cells in Rabbit Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO
• Can be cultured at least 6 doublings

Please refer to the RbAOSMC Culture Protocol.

Other Notes

Rabbit Smooth Muscle Cell Basal Medium that contains 10% FBS and 10% DMSO

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable