S128

N-Methylspiperone hydrochloride

solid

• Synonym(e): N-Methyl-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro-[4.5]decan-4-one hydrochloride
• Empirische Formel (Hill-System): C₂₄H₂₈FN₃O₂ · HCl
• CAS-Nummer: 87539-19-3
• Molekulargewicht: 445.96
• NACRES: NA.77
• PubChem Substance ID: 24899471
• UNSPSC Code: 12352200
• MDL number: MFCD00083200

Eigenschaften

• form: solid
• Quality Segment: 100
• color: light yellow
• solubility: 0.1 M HCl: soluble, ethanol: soluble
• SMILES string: Cl.CN1CN(c2ccccc2)C3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)C1=O
• InChI: 1S/C24H28FN3O2.ClH/c1-26-18-28(21-6-3-2-4-7-21)24(23(26)30)13-16-27(17-14-24)15-5-8-22(29)19-9-11-20(25)12-10-19;/h2-4,6-7,9-12H,5,8,13-18H2,1H3;1H
• InChI key: OGOQOKYYPNFSOL-UHFFFAOYSA-N

Beschreibung

General description

N-Methylspiperone acts as a D2 dopamine receptor antagonist. It is an analog of spiperone. The isotope 3-N-[¹¹C]methylspiperone ([¹¹C]NMSP) is widely used in dopamine receptor imaging in positron emission tomography (PET).

Application

Reference standard.

Biochem/physiol Actions

D₂ dopamine receptor antagonist.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• PSA (Persönliche Schutzausrüstung): Eyeshields, Gloves, type N95 (US)