S4701

Suplatast tosylate

≥98% (HPLC)

• Synonym(e): (+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate, IPD-1151T, ST
• Empirische Formel (Hill-System): C₁₆H₂₆SNO₄ · C₇H₇SO₃
• CAS-Nummer: 94055-76-2
• Molekulargewicht: 499.64
• NACRES: NA.77
• PubChem Substance ID: 329824551
• UNSPSC Code: 12352200
• MDL number: MFCD00867604
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• solubility: DMSO: >20 mg/mL
• storage temp.: room temp
• SMILES string: Cc1ccc(cc1)S([O-])(=O)=O.CCOCC(O)COc2ccc(NC(=O)CC[S+](C)C)cc2
• InChI: 1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)
• InChI key: RYVJQEZJUFRANT-UHFFFAOYSA-N

Beschreibung

Application

Suplatast tosylate may be used in immune-signaling studies.

Biochem/physiol Actions

Suplatast tosylate is a dimethylsulfonium compound downregulates the expression of histamine H₁ receptor gene, suppresses the activity of histidine decarboxylase and regulates IL-4 mRNA. It inhibits the release of histamines and regulates the production of IgE.^1,2 Suplatast tosylate is effective in the treatment of mild-to-moderate persistent asthma in children.³

Suplatast tosylate is an anti-allergy, cytokine modulator.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable