SML0216

Brinzolamid

≥98% (HPLC)

• Synonym(e): (R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazin-6-sulfonamid-1,1-dioxid
• Empirische Formel (Hill-System): C₁₂H₂₁N₃O₅S₃
• CAS-Nummer: 138890-62-7
• Molekulargewicht: 383.51
• NACRES: NA.77
• PubChem Substance ID: 329825236
• UNSPSC Code: 12352200
• MDL number: MFCD08067749
• eCl@ss: 32150313
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: ≥10 mg/mL
• storage temp.: −20°C
• SMILES string: CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O
• InChI: 1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1
• InChI key: HCRKCZRJWPKOAR-JTQLQIEISA-N
• Gene Information: human ... CA2(760)

Beschreibung

General description

Brinzolamide is a small molecular weight compound that has an ability to bind melanin. This drug is used in ocular therapy.

Application

Brinzolamide has been used as a melanin binding compound or drug in melanin binding assays. It has also been used as a carbonic anhydrase inhibitor (CAI).

Biochem/physiol Actions

Brinzolamide is a carbonic anhydrase II inhibitor

Brinzolamide is a carbonic anhydrase II inhibitor used to lower intraocular pressure.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable