SML0235

CDPPB

≥98% (HPLC)

• Synonym(e): 3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide
• Empirische Formel (Hill-System): C₂₃H₁₆N₄O
• CAS-Nummer: 781652-57-1
• Molekulargewicht: 364.40
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825248
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: ≥5 mg/mL at warmed to 60 °C
• storage temp.: 2-8°C
• SMILES string: O.O=C(Nc1cc(nn1-c2ccccc2)-c3ccccc3)c4cccc(c4)C#N
• InChI: 1S/C23H16N4O.H2O/c24-16-17-8-7-11-19(14-17)23(28)25-22-15-21(18-9-3-1-4-10-18)26-27(22)20-12-5-2-6-13-20;/h1-15H,(H,25,28);1H2
• InChI key: GZHZEGYXLNXEBV-UHFFFAOYSA-N

Beschreibung

Application

CDPPB may be used in mGluR5-mediated cell signaling studies.

Biochem/physiol Actions

CDPPB is a glutamate metabotropic mGluR5 positive allosteric modulator.

CDPPB is an mGluR5 positive allosteric modulator

Activation of metabotropic glutamate 5 receptor by CDPPB enhances the function of NMDA receptor and markers of neuronal plasticity. This improves recognition memory and cognition deficits in schizophrenia.

Features and Benefits

This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable