SML1052

2-D08

≥98% (HPLC)

• Synonym(e): 2′,3′,4′-trihydroxy-flavone, 2-(2,3,4-Trihydroxyphenyl)-4H-1-Benzopyran-4-one
• Empirische Formel (Hill-System): C₁₅H₁₀O₅
• CAS-Nummer: 144707-18-6
• Molekulargewicht: 270.24
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [o]1c2c([c](cc1c3c(c(c(cc3)O)O)O)=O)cccc2
• InChI: 1S/C15H10O5/c16-10-6-5-9(14(18)15(10)19)13-7-11(17)8-3-1-2-4-12(8)20-13/h1-7,16,18-19H
• InChI key: JJAXTFSPCLZPIW-UHFFFAOYSA-N

Beschreibung

Application

2-D08 has been used as a small ubiquitin-like modifier (SUMO)ylation inhibitor.

Biochem/physiol Actions

2-D08 is a potent and cell-permeable inhibitor of sumoylation that block the transfer of SUMO (small ubiquitin-like modifier) from the E2 enzyme (Ubc9) thioester conjugate to the substrate.

2-D08 is a potent and cell-permeable inhibitor of sumoylation.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable