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SML1689
Eupatilin
from (Isolated from Artemisia sp.), ≥98% (HPLC), powder, lipophilic flavonoid
Synonym(e):
2-(3,4-Dimethoxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one, 5,7-Dihydroxy-3′,4′,6-trimethoxyflavone, NSC 122413
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| Größe/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 110,00 |
25 mg | Warenkorb auf Verfügbarkeit prüfen | € 444,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C18H16O7
CAS-Nummer:
Molekulargewicht:
344.32
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated, protect from light
Technischer Dienst
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Unterstützung erhaltenProduktname
Eupatilin, ≥98% (HPLC)
biological source
(Isolated from Artemisia sp.)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated, protect from light
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C31
InChI
1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3
InChI key
DRRWBCNQOKKKOL-UHFFFAOYSA-N
Application
Eupatilin has been used to investigate its inhibitory effects on intracranial hemorrhage (ICH)-induced inflammation and its anti-inflammatory mechanisms in mouse BV2 cells, in vitro. It has also been used as a standard for its quantitative estimation in Artemisia extracts by microcolumn high performance liquid chromatography with diode array (HPLC-DAD) assay.
Biochem/physiol Actions
Eupatilin is a flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties.
Flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties
Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis.
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Dieser Artikel | |||
|---|---|---|---|
| description ≥98% (HPLC) | description phyproof® Reference Substance | description ≥97% (HPLC) | description phyproof® Reference Substance |
| form powder | form - | form powder | form solid |
| assay ≥98% (HPLC) | assay ≥95.0% (HPLC) | assay ≥97% (HPLC) | assay ≥90.0% (HPLC) |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level - |
| storage temp. −20°C | storage temp. - | storage temp. room temp | storage temp. - |
| solubility DMSO: 20 mg/mL, clear | solubility - | solubility DMSO: >10 mg/mL | solubility - |
| storage condition desiccated, protect from light | storage condition - | storage condition - | storage condition - |
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Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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