SML2127

Dynapyrazole-A

≥98% (HPLC)

• Synonym(e): 2-[1-(4-Chloro-phenyl)-cyclopropyl]-7-iodo-5-oxo-4,5-dihydro-pyrazolo[1,5-a]quinazoline-3-carbonitrile
• Empirische Formel (Hill-System): C₂₀H₁₂ClIN₄O
• CAS-Nummer: 2226517-75-3
• Molekulargewicht: 486.69
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (warmed)
• storage temp.: 2-8°C
• SMILES string: IC1=CC=C(N2C(NC3=O)=C(C#N)C(C4(CC4)C5=CC=C(Cl)C=C5)=N2)C3=C1
• InChI: 1S/C20H12ClIN4O/c21-12-3-1-11(2-4-12)20(7-8-20)17-15(10-23)18-24-19(27)14-9-13(22)5-6-16(14)26(18)25-17/h1-6,9H,7-8H2,(H,24,27)
• InChI key: VABPBCMFKJDOHP-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Dynapyrazole-A is a potent dynein inhibitor. Dynapyrazole-A inhibits microtubule activity without inhibiting basal ATPase activity.

Dynein inhibitor

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable